Prolactin secretion after generalized after generalized seizures (38 patients), complex partial seizures (7) and febrile convulsions (14) was studied in a group of children aged between 2 months and 13 years.
In these studies, seizure classification was made from the observer's descriptions. Serum Seum prolactin levels were determined within 1 hour after the control of seizure attacks .
Out of 38 generalized seizure cases, 37 were followed by a significant increase in prolactin concentration (mean, male 36.0±18.6ng/ml, female 34.5±13.7ng/ml ; range 9.2 to 110ng/ml) compared with febrrile convulsions (mean, male 20.5±7.9ng/ml,
female
13.7±5.5ng/ml ; range, 6.5 to 34.1ng/ml)
The data indicated that serum prolactin levels rise after generalized seizures and thus, measurement of the postictal prolactin levels can help identify the generalized seizures.
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